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KMID : 0881720160310050380
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Journal of Food Hygiene and Safety
2016 Volume.31 No. 5 p.380 ~ p.385
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Antibacterial Property of Ecklonia cava Extract against Marine Bacterial Pathogens
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Kim Ji-Hoon
Hwang Hye-Jin
Kim Young-Mog
Kim Se-Bong
Lee Myung-Suk
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Abstract
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The object of this study was to evaluate antibacterial activity of edible seaweed extracts against marine bacterial pathogens including Edwardsiella tarda, Streptococcus iniae, Streptococcus parauberis, Vibrio anguillarum, Vibiro harveyi and Vibrio scophthalm, which are associated with human or fish infectious disease. Ecklonia cava methanolic extract showed a strong and broad spectrum antibacterial activity against marine bacterial pathogens used in this study. Among solvent-soluble fractions of the E. cava extract, the ethyl acetate (EtOAc) soluble fraction showed the strongest antibacterial activity against marine bacterial pathogens tested in this study with MIC in the range of 128-256 μg/mL. Furthermore, HPLC analysis revealed that the soluble fraction contains abundant dieckol, a phlorotannin compound, compared to other solvent soluble fractions, suggesting that phlorotannins including dieckol would be a key antibacterial agent against marine bacterial pathogens.
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KEYWORD
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antibacterial activity, phlorotannins, Ecklonia cava, marine bacterial pathogens
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